Pulmonary News

Physical distancing interventions shows moderate reduction of incidence of coronavirus disease 2019 with caveats: natural experiment in 149

Objective : To evaluate the association between physical distancing interventions and incidence of coronavirus disease 2019 (covid-19) globally. Design : Natural experiment using interrupted time series analysis, with results synthesised using meta-analysis. Setting : 149 countries or regions, with data on daily reported cases of covid-19 from the European Centre for Disease Prevention and Control [...]

Physical distancing interventions shows moderate reduction of incidence of coronavirus disease 2019 with caveats: natural experiment in 1492020-08-08T12:08:24-04:00

Use of N95, Surgical, and Cloth Masks to Prevent COVID-19 in Health Care and Community Settings: Living Practice Points From the American College of Physicians

Regardless of the use of respiratory PPE, other procedures to reduce the transmission of SARS-CoV-2 infection should be followed, including maintaining physical distance, self-isolation, quarantine, frequent hand hygiene (using soap and water or alcohol-based hand rub), covering coughs and sneezes by using a bent elbow or paper tissue, refraining from touching the face, and frequent [...]

Use of N95, Surgical, and Cloth Masks to Prevent COVID-19 in Health Care and Community Settings: Living Practice Points From the American College of Physicians2020-08-01T12:55:12-04:00

Promising Early Data from New COVID-19 Vaccine Studies Showing Safety and potential Efficacy

Around the world, more than 100 candidate vaccines against SARS-CoV-2 are in various stages of development and testing. On May 18, US biotech firm Moderna revealed the first data from a human trial: its COVID-19 vaccine triggered an immune response in people, and protected mice from lung infections with the coronavirus SARS-CoV-2. The current study [...]

Promising Early Data from New COVID-19 Vaccine Studies Showing Safety and potential Efficacy2020-07-25T13:33:05-04:00

Hydroxychloroquine and Azithromycin use in COVID-19 :Final chapter is not written yet

Over the last few months several studies has shown conflicting efficacy and safety of Hydroxychloroquine (HCQ) alone or in association with azithromycin or Doxycycline. Most recent data now published in International Journal of Infectious Diseases showing mortality benefit of HCQ alone or in association with Azithromycin in the treatment of COVID-19. In this observational study [...]

Hydroxychloroquine and Azithromycin use in COVID-19 :Final chapter is not written yet2020-07-18T12:14:08-04:00

Yale Treatment Algorithm for Hospitalized ADULTS with Non – Severe* COVID-19

Yale Ad-Hoc COVID-19 Treatment Team algorithms and protocols - multiple algorithms are assembled into a series of color-coded guidance sheets for hospitalist and internist to use. This algorithm is last updated on 4/27/20 and as such still include Hydroxychloroquine in treatment pathway, which is not a standard of care currently. However, rest of the treatment [...]

Yale Treatment Algorithm for Hospitalized ADULTS with Non – Severe* COVID-192020-07-11T23:44:12-04:00

Study: Mysterious vaping lung injuries may have flown under regulatory radar

It was the arrival of the second man in his early 20s gasping for air that alarmed Dixie Harris, MD. Young patients rarely get so sick, so fast, with a severe lung illness, and this was her second case in a matter of days. Then she saw three more patients at her Utah telehealth clinic [...]

Study: Mysterious vaping lung injuries may have flown under regulatory radar2019-09-06T08:18:39-04:00

The Caveat to Inhaled Corticosteroids for Asthma

For the past several years, the trend has been to use inhaled corticosteroid(ICS) early and often for patients with asthma. And now the 2019 Global Initiative for Asthma (GINA) guidelines recommend using ICS as first-line therapy (step 1) as needed).[1] This change is sure to increase ICS use even more. The logic behind using ICS [...]

The Caveat to Inhaled Corticosteroids for Asthma2019-09-03T03:37:31-04:00

Obstructive sleep apnea: focus on myofunctional therapy

PURPOSE: Orofacial myofunctional therapy (OMT) is a modality of treatment for children and adults with obstructive sleep apnea (OSA) to promote changes in the musculature of the upper airways. This review summarizes and discusses the effects of OMT on OSA, the therapeutic programs employed, and their possible mechanisms of action. METHODS: We conducted an online [...]

Obstructive sleep apnea: focus on myofunctional therapy2019-03-07T09:36:49-05:00

Obstructive sleep apnea: Who should be tested, and how?

Patients who have risk factors for obstructive sleep apnea (OSA) or who report symptoms of OSA should be screened for it, first with a complete sleep history and standardized questionnaire, and then by objective testing if indicated. The gold standard test for OSA is polysomnography performed overnight in a sleep laboratory. Home testing is an [...]

Obstructive sleep apnea: Who should be tested, and how?2019-03-07T09:38:18-05:00

Lies, Damned Lies, and Asthma

Aminophylline suppositories, cocaine nasal packs, and potassium iodide were commonly prescribed for asthma in 1963 when Claude A. Frazier, MD, wrote a thoughtful essay on the do’s and don’ts in treating allergic asthma in Consultant.1 How times have changed! Dr Frazier left us with several clinical observations that are prophetic. He was correct in asserting [...]

Lies, Damned Lies, and Asthma2019-01-11T09:38:03-05:00